Arthrosamid Injections/Hydrogels

Arthrosamid is a cutting-edge injectable that offers long-lasting pain relief for knee osteoarthritis.

At a glance

About

A non-invasive treatment for degenerative knee osteoarthritis

Effective
Referrals

Not Needed

Booking

Instant-book option available

Cost
£ 2995
  • Lincolnshire £ 2995

Nature of knee cartilage injuries

Knee cartilage injuries are a common cause of knee pain and discomfort, particularly in patients with osteoarthritis. Unlike bone and muscle tissues, cartilage lacks a direct blood supply, which significantly limits its ability to repair itself.

When the cartilage in the knee joint is damaged, it may lead to pain, swelling, inflammation, and reduced mobility. Over time, if left untreated, cartilage damage can progress and worsen, contributing to the development of osteoarthritis.

Common causes of knee cartilage injuries

Knee cartilage injuries often result from repetitive stress on the knee joint or traumatic events, including:

High-impact activities: Running, jumping, or heavy lifting can place stress on the knee joint, leading to cartilage wear and injury.

Previous knee injuries: Fractures, ligament tears, or meniscus damage can increase the risk of cartilage damage as the joint structure is altered.

Ageing: As we age, the cartilage naturally weakens and becomes more prone to damage due to wear and tear.

Obesity: Excess body weight can place increased pressure on the knee joints, accelerating cartilage degradation.

Genetic predisposition: Some individuals may be more susceptible to cartilage injuries due to their genetic makeup, making them more prone to joint problems.

Diagnosing knee cartilage injuries

Knee cartilage injuries often present with pain, swelling, and limited range of motion. Patients may also report clicking, locking, or catching sensations in the joint. Diagnosis typically begins with a physical exam to assess pain, tenderness, and mobility. Imaging tests like X-rays or MRIs are commonly used to visualise the joint, assess the extent of cartilage damage, and guide treatment planning.

Suitable for

Treatment overview

Arthrosamid (a hydrogel) is an innovative treatment for knee osteoarthritis. It works by reducing inflammation around the joint, which is a key contributor to both knee pain and disease progression.

Arthrosamid is supported by more than two decades of research. It is proven to be safe and effective, offering long-lasting pain relief. The hydrogel is administered via a simple, one-step procedure under local anaesthetic. There is no need for complex surgeries, you can be in and out of our treatment centre on the same day.

MSK were the 1st to do in the UK have done over 500, have our own protocol for injection with good success rate and low complication rate. We have published and presented our results at international and nation conference.

About the product

Arthrosamid is a non-degradable and non-resorbable hydrogel composed of 2.5% cross-linked polyacrylamide and 97.5% non-pyrogenic water (McCollister et al., 1965). It is administered via an intra-articular injection into the knee joint.

The hydrogel serves as a scaffold for the synovial membrane, binding to the synovial membrane and acting as a physical buffer and scaffold.

Benefits

No long-lasting adverse effects have been reported in clinical studies

Positive effects have been shown to last for at least 2 years

Clinical studies have highlighted the efficiency of Arthrosamid, especially compared to traditional treatments like hyaluronic acid

MSK Doctors

We’re an MSK specialist clinic, made up of a team of doctors who focus on musculoskeletal health. We take the time to recommend the best treatment for our patients, not just the simplest or quickest.

We specialise in cutting-edge, alternative treatments, helping our patients alleviate pain and injury, without the need for surgery. Whilst the success of Arthrosamid is widely-reported, we also offer a range of complementary treatments that might further improve your condition.

How to pay

Self-pay

Most patients choose to self-fund their treatment by:

Bank transfers
Credit/debit cards
Cash (in person only)

Private medical insurance

Some of our treatments are covered by private medical insurance, check with your specific provider for more information.

Payment options

We partner with Kandoo, if you would like to pay in instalments. Head to the Kandoo page to make a finance application. You’ll receive an instant decision and your credit score will not be impacted.

The booking process

Online booking/call

Use our Calendly to book an initial consultation, or give us a call.

01

consultation

If you are a new patient, our doctors might arrange a consultation before treatment.

02

Treatment

You will be booked in for treatment. You will be booked in for treatment.

03

Follow up

Our doctors might arrange a follow-up consultation, to check your response to treatment.

04

Discharge

Once your doctor is happy with your recovery, you will be discharged. After discharge, we are always here for further questions or support, should you need it.

05

Frequently asked questions

How does Arthrosamid work?
  • It integrates with the knee’s existing synovial fluid, enhancing its ability to protect and lubricate the joint surfaces.
  • This can lead to significant pain reduction and improved joint mobility.

Patients may notice an improvement in knee pain and mobility within a few weeks. The full effects can take several weeks to be realized as the hydrogel integrates with the joint tissue.

Injection Treatment Comparison

Explore the key differences between leading injection therapies used in joint, tendon, and cartilage care. Compare their effectiveness, uses, recovery time, and potential drawbacks to help guide your treatment decisions.

Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
Hyaluronic Acid (HA) Injection
Mild to moderate knee osteoarthritis, joint lubrication
⭐⭐⭐
Lubricates joints, reduces friction, and relieves pain in osteoarthritis.
Immediate return to daily activities, effects last 3-12 months.
Short-term relief, effects wear off over time; does not regenerate cartilage.
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
Cartilage Matrix Injection
Moderate to severe cartilage damage, osteoarthritis, surgical augmentation
⭐⭐⭐⭐⭐
Provides a structural scaffold to support cartilage repair and regeneration.
Minimal downtime, improvement in 4-6 weeks, lasting 6-12 months.
May lead to mild inflammation or combination with other therapies for best results
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
PRP (Platelet-Rich Plasma) Injection
Tendon injuries, mild arthritis, post-surgical healing.
⭐⭐⭐
Uses growthregfactors from the patient’s own blood to stimulate healing and reduce inflammation. Work well on ligaments and tendons.
Minimal downtime, improvement seen in 4-6 weeks, lasting 6-12 months.
Not very effective for established Arthritis. Unless combined with other treatments.
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
PRP (Platelet-Rich Plasma) Injection
Tendon injuries, mild arthritis, post-surgical healing.
⭐⭐⭐
Uses growthregfactors from the patient’s own blood to stimulate healing and reduce inflammation. Work well on ligaments and tendons.
Minimal downtime, improvement seen in 4-6 weeks, lasting 6-12 months.
Not very effective for established Arthritis. Unless combined with other treatments.
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
mFAT (Microfragmented Adipose Tissue) Injection
Moderate to severe arthritis, joint degeneration, soft tissue repair
⭐⭐⭐⭐
Fat-derived stem cells injected into joints to reduce inflammation and promote tissue repair.
Light activity immediately, pain relief in 2-4 weeks, lasting 6-24 months
Requires minor liposuction to harvest fat; may not be as effective in severe arthritis
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
BMAC (Bone Marrow Aspirate Concentrate) Injection
Fracture healing. Previously used for cartilage regeneration; less preferred due to inconsistent results
⭐⭐
Bone marrow cells injected for potential cartilage repair, but effectiveness varies.
Minimal restrictions, noticeable effects in 3 months, full benefits in 6-12 months.
Inconsistent results, Very invasive; less preferred compared to other regenerative options.
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
Cortisone (Steroid) Injection
Severe inflammation, advanced arthritis pain management (short-term use only)

(Anti-Inflammatory)
Powerful anti-inflammatory, provides temporary pain relief but accelerates joint degeneration.
Immediate pain relief, but potential long-term cartilage damage. Best when mixed with PRP & HA to reduce toxicity.
Toxic to cartilage; long-term use can accelerate joint degeneration.
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
Exosome Injection
Early-stage arthritis, tendon injuries, inflammation modulation, post-surgical recovery.
⭐⭐⭐
Delivers signaling molecules that promote regeneration, reduce inflammation, and support healing at a cellular level.
Minimal downtime, improvement seen in 3-6 weeks, lasting 6-12 months.
Still experimental; effectiveness varies depending on the condition treated.
Injection Type
Best For
Effectiveness
(⭐ out of 5)
What It Does
Recovery Time
Downside
Hyaluronic Acid (HA) Injection
Mild to moderate knee osteoarthritis, joint lubrication
⭐⭐⭐
Lubricates joints, reduces friction, and relieves pain in osteoarthritis.
Immediate return to daily activities, effects last 3-12 months.
Short-term relief, effects wear off over time; does not regenerate cartilage.
Cartilage Matrix Injection
Moderate to severe cartilage damage, osteoarthritis, surgical augmentation
⭐⭐⭐⭐⭐
Provides a structural scaffold to support cartilage repair and regeneration.
Minimal downtime, improvement in 4-6 weeks, lasting 6-12 months.
May lead to mild inflammation or combination with other therapies for best results
Arthrosamid Injection (Hydrogel)
Moderate to severe knee osteoarthritis, locking in regeneration effects, shielding the synovium
⭐⭐⭐⭐
(Anti-degeneration)
Does not regenerate cartilage but indirectly reduces inflammation and protects the joint.
Immediate return to activities, full effect in 2-4 weeks, lasts 12-24 months
Does not regenerate cartilage, only helps maintain improvements and Side effect profile.
PRP (Platelet-Rich Plasma) Injection
Tendon injuries, mild arthritis, post-surgical healing.
⭐⭐⭐
Uses growthregfactors from the patient’s own blood to stimulate healing and reduce inflammation. Work well on ligaments and tendons.
Minimal downtime, improvement seen in 4-6 weeks, lasting 6-12 months.
Not very effective for established Arthritis. Unless combined with other treatments.
mFAT (Microfragmented Adipose Tissue) Injection
Moderate to severe arthritis, joint degeneration, soft tissue repair
⭐⭐⭐⭐
Fat-derived stem cells injected into joints to reduce inflammation and promote tissue repair.
Light activity immediately, pain relief in 2-4 weeks, lasting 6-24 months
Requires minor liposuction to harvest fat; may not be as effective in severe arthritis
BMAC (Bone Marrow Aspirate Concentrate) Injection
Fracture healing. Previously used for cartilage regeneration; less preferred due to inconsistent results
⭐⭐
Bone marrow cells injected for potential cartilage repair, but effectiveness varies.
Minimal restrictions, noticeable effects in 3 months, full benefits in 6-12 months.
Inconsistent results, Very invasive; less preferred compared to other regenerative options.
Cortisone (Steroid) Injection
Severe inflammation, advanced arthritis pain management (short-term use only)

(Anti-Inflammatory)
Powerful anti-inflammatory, provides temporary pain relief but accelerates joint degeneration.
Immediate pain relief, but potential long-term cartilage damage. Best when mixed with PRP & HA to reduce toxicity.
Toxic to cartilage; long-term use can accelerate joint degeneration.
Exosome Injection
Early-stage arthritis, tendon injuries, inflammation modulation, post-surgical recovery.
⭐⭐⭐
Delivers signaling molecules that promote regeneration, reduce inflammation, and support healing at a cellular level.
Minimal downtime, improvement seen in 3-6 weeks, lasting 6-12 months.
Still experimental; effectiveness varies depending on the condition treated.
Best For

Mild to moderate knee osteoarthritis, joint lubrication

What It Does

Lubricates joints, reduces friction, and relieves pain in osteoarthritis.

Recovery Time

Immediate return to daily activities, effects last 3-12 months.

Downside

Short-term relief, effects wear off over time; does not regenerate cartilage.

Best For

Moderate to severe cartilage damage, osteoarthritis, surgical augmentation

What It Does

Provides a structural scaffold to support cartilage repair and regeneration.

Recovery Time

Minimal downtime, improvement in 4-6 weeks, lasting 6-12 months.

Downside

May lead to mild inflammation or combination with other therapies for best results

Best For

Tendon injuries, mild arthritis, post-surgical healing.

What It Does

Uses growthregfactors from the patient’s own blood to stimulate healing and reduce inflammation. Work well on ligaments and tendons.

Recovery Time

Minimal downtime, improvement seen in 4-6 weeks, lasting 6-12 months.

Downside

Not very effective for established Arthritis. Unless combined with other treatments.

Best For

Tendon injuries, mild arthritis, post-surgical healing.

What It Does

Uses growthregfactors from the patient’s own blood to stimulate healing and reduce inflammation. Work well on ligaments and tendons.

Recovery Time

Minimal downtime, improvement seen in 4-6 weeks, lasting 6-12 months.

Downside

Not very effective for established Arthritis. Unless combined with other treatments.

Best For

Moderate to severe arthritis, joint degeneration, soft tissue repair

What It Does

Fat-derived stem cells injected into joints to reduce inflammation and promote tissue repair.

Recovery Time

Light activity immediately, pain relief in 2-4 weeks, lasting 6-24 months

Downside

Requires minor liposuction to harvest fat; may not be as effective in severe arthritis

Best For

Fracture healing. Previously used for cartilage regeneration; less preferred due to inconsistent results

What It Does

Bone marrow cells injected for potential cartilage repair, but effectiveness varies.

Recovery Time

Minimal restrictions, noticeable effects in 3 months, full benefits in 6-12 months.

Downside

Inconsistent results, Very invasive; less preferred compared to other regenerative options.

Best For

Severe inflammation, advanced arthritis pain management (short-term use only)

What It Does

Powerful anti-inflammatory, provides temporary pain relief but accelerates joint degeneration.

Recovery Time

Immediate pain relief, but potential long-term cartilage damage. Best when mixed with PRP & HA to reduce toxicity.

Downside

Toxic to cartilage; long-term use can accelerate joint degeneration.

Best For

Early-stage arthritis, tendon injuries, inflammation modulation, post-surgical recovery.

What It Does

Delivers signaling molecules that promote regeneration, reduce inflammation, and support healing at a cellular level.

Recovery Time

Minimal downtime, improvement seen in 3-6 weeks, lasting 6-12 months.

Downside

Still experimental; effectiveness varies depending on the condition treated.

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